24 articles - From Friday Apr 11 2025 to Friday Apr 18 2025
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
| Pancreas |
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Endoscopic and Surgical Treatments for Painful Chronic Pancreatitis: A Scoping Review of Pain Assessment Tools and Meta-analysis of Outcomes. Pain outcomes were similar between endotherapy and surgery for painful CP based on the use of simple and highly variable pain assessment tools. Referral bias and sham effects need to be considered in future trials. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
|---|
Association of meal timing with adiposity measures and gut microbiome characteristics in a cohort study: the Hispanic Community Health Study/Study of Latinos. Shorter EW may promote healthy weight, but some individuals with longer vs shorter EWs tend to have greater activity that could balance their greater energy intake. EW and EWC may influence GMB characteristics. |
Dietary intake of poly-unsaturated fatty acids, their food sources and fertility in females and males: a preconception prospective population-based cohort study. In females, higher dietary omega-3 PUFAs intake may benefit fertility. Increased nuts and seeds consumption may improve fertility in males, independent of PUFA intake. These findings suggest potential for gender-specific dietary interventions to support reproductive health. |
Exploring the acute and chronic effects of a multi-strain probiotic supplement on cognitive function and mood in healthy older adults: A randomised controlled trial. The current work provides novel evidence for an acute effect of probiotics on reaction times during executive function, which should be replicated in future work. Additionally, this work replicates previous findings of improved cognitive reactivity to sad mood following chronic probiotic supplementation, indicating probiotics may reduce the risk of developing depression in a healthy ageing population. |
Impact of High- and Moderate- Protein Supplementation on Early-life Obesity and Body Composition : A Randomized Controlled Trial in India. High-protein supplementation from 6 to 12 months did not increase fat accretion or obesity risk at 24 months. Nutritional interventions in LMICs should prioritize both protein quality and overall dietary balance to simultaneously prevent undernutrition and excess weight gain. Clinical trial registry number and website |
Perspective: Operation Stork Speed: Strategies for reviewing and advising on infant formula. This initiative has the potential to update many aspects of infant formula content and evaluation but will require an extensive process including numerous federal agencies and the private sector. No one group, including the Food and Drug Administration (FDA), has the capacity to perform this evaluation by itself and no simplified process of obtaining comments from the public can adequately allow for a full and unbiased review and recommendations. |
| Inflamm Bowel Dis |
A Multicenter Study to Assess Avoidant/Restrictive Food Intake Disorder in Patients with Inflammatory Bowel Disease. In this multi-center study, 16.3% of patients with inactive IBD met the criteria for ARFID, and 17.8% of al patients met the criteria regardless of objective disease activity. GI-specific anxiety was the only predictor of ARFID among patients with inactive IBD, highlighting the need for multidisciplinary care in IBD. |
Akkermansia muciniphila Protects Against Trinitrobenzene Sulfonic Acid Induced Colitis by Inhibiting IL6/STAT3 Pathway. Our findings declared that A. muciniphila supplementation alleviates gastrointestinal inflammation through IL-6/STAT3 signaling pathway. This protective effect was mediated by the downregulation of the IL-6 and STAT3, highlighting a potential mechanism by which A. muciniphila modulates inflammatory responses. This work disclosed that A. muciniphila demonstrates a defensive influence against TNBS-induced enteritis in vivo, proposing it qualified as a unique therapeutic focusing on modulating IL-6, STAT3, or p-STAT3 in the treatment of colitis. |
Increased Colonic Levels of CD8+ Cytotoxic T lymphocyte-Associated Mediators in Patients With Microscopic Colitis. Microscopic colitis patients exhibit increased levels of several analytes, including some associated with CD8+ T lymphocytes, suggesting a different pathogenesis of MC compared to UC. Higher levels of MMP-1 and MMP-3 in CC than LC indicate separate disease entities. |
Safety Outcomes in Patients With Ulcerative Colitis Using a Healthcare Administrative Database in the United States. These findings assist in understanding the background risks of safety events in patients with UC and suggest that the incidence of select safety outcomes is comparable between the ELEVATE UC trials and RWD. |
| J Crohns Colitis |
Drug tissue concentration and STAT3 modulation as determinants of tofacitinib response in ulcerative colitis. This study underscores the importance of tissue tofacitinib levels in UC treatment efficacy, with pSTAT3 reduction serving as a potential marker of drug efficacy. RNA sequencing identified molecular pathways for potential biomarkers and novel therapeutic targets in tofacitinib non-responders. |
Subcutaneous Infliximab (CT-P13 SC) as Maintenance Therapy for Crohn's Disease and Ulcerative Colitis: 2-Year Results from Open-Label Extensions of Two Randomized Controlled Trials (LIBERTY). CT-P13 SC is an effective and well-tolerated long-term maintenance treatment in moderate-to-severe CD and UC. |
| Pancreas |
Factors Driving Pancreatic Cancer Survival Rates. Importantly, since only 14% of patients are diagnosed at this stage, the survival rate for most patients remains unchanged. This work also emphasizes the need for more research around variables that influence the overall 5-year survival rate, along with greater investment in early detection strategies to improve patient survival. |
NAMPT Modulates Gemcitabine Resistance in Pancreatic Cancer via the p53 Signaling Pathway. These findings suggest that NAMPT could serve as a promising therapeutic target to overcome gemcitabine resistance in PDAC, laying the groundwork for future clinical investigations aimed at modulating nicotinate and nicotinamide metabolism to improve treatment outcomes. |
Serum 25-Hydroxyvitamin D and Vitamin D Receptor Genetic Polymorphisms are Associated with Prognosis of Acute Pancreatitis. VD deficiency and VDR genetic polymorphisms are associated with AP prognosis in Chinese Han patients with AP. VDR genetic polymorphism may influence the outcomes of AP patients by affecting the levels of inflammatory cytokines. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Inflamm Bowel Dis |
|---|
misc publications eg case reports, tools of the trade, images of the month, etc…
| Am J Clin Nutr |
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| Inflamm Bowel Dis |
| J Crohns Colitis |